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  • Both the number of prescriptions filled per 1,000 residents and the morphine milligram equivalent (MME) per resident per year decreased since 2010.  These decreases reflect a decline in the number of prescriptions per person or in pills per prescription.
    • The rate of prescriptions dispensed in California dropped 25% between 2010 and 2018 (from 607 to 457 per 1,000 residents).
    • The total number of prescriptions dispensed in California has dropped 14% from 23 million in 2010 to 19.8 million in 2018.
    • The average MME decreased by half – 50% – from 693 MME per resident per year in 2010 to 349 per resident per year in 2018.
  • Prescription opioid-related overdose deaths (excluding synthetics) in California peaked in 2009 at 1,483 deaths and have decreased to 1,047 in 2018, a 29% decrease. The age-adjusted rate of prescription opioid-related deaths (excluding synthetics) in 2018 was 2.5 per 100,000 California residents.
  • Heroin-related overdose deaths have increased 107% since 2012 from 361 (.91 per 100,000) to 749 (1.8 per 100,000) in 2018.
  • Fentanyl-related overdose deaths have shown an even steeper 806% increase from 82 in 2012 to 743 in 2018.
  • Amphetamine-related overdose deaths have increased 198% from 777 in 2012 to 2,316 in 2018.